Ces radiol. 2007, 61(2):138-145

Long term results of angioplasty of renal graft arteryOriginal article

Jan H Peregrin¹, Jarmila Stříbrná¹, Jiří Lácha², Jelena Skibová³

¹ Základna radiodiagnostiky a intervenční radiologie IKEM, Praha

² Klinika nefrologie IKEM, Praha

³ Oddělení statistiky IKEM, Praha

Aim: To evaluate long-term effect of renal angioplasty (PTRA) on hypertension and renal function in subjects with renal artery stenosis of transplanted kidney (TRAS).

Method: Within a 24-year-period, 58 PTRAs in 55 adults (3 times Re-PTRA) with transplanted kidney were performed. The group included 34 males and 21 females, average age 41 ± 10.6 (18-72) years. After exclusion of 7 technical failures, 51 PTRAs were followed at one week, six months, one, two and three years after PTRA. Hypertension improvement was defined as mean arterial pressure (MAP) decrease of at least 15 % from the pre-PTRA value. Graft function was evaluated by serum creatinine (Scr) and creatinine clearance (Ccr) levels, and the improvement was defined as a 20 % change.

Results: Technical success of PTRA was 88.4 %. Among 51 kidney recipients at the end of FU, blood pressure improved in 65.2 % (MAP decreased from 123 ± 13.1 to 107 ± 12.1 mm Hg), but no patient remained normotensive without medication. Graft function improved in 44.8 % of patients and was stabilized in 27.6 % of them (average Ccr before PTRA: 0.48 ± 0.29, after PTRA: 0.78 ± 0.47 ml/s). PTRA complications were observed in 25.5 % of procedures, most often with no clinical sequel. Thirty days mortality was 1.8 % (one patient).

Conclusion: PTRA in kidney recipients is valuable mainly for preserving graft function.

Keywords: percutaneous transluminal angioplasty, posttransplant hypertension, kidney graft failure, transplanted kidney artery stenosis, transplanted kidney

Grants and funding:

Podporováno Výzkumným záměrem IKEM (MZO 0023001).

Accepted: April 15, 2007; Published: June 1, 2007  Show citation