Ces radiol. 2011, 65(1):51-60

Imaging of the bone metastase with 18F-NaF-PET/CTReview article

Eva Ferdová1, Jiří Ferda1, Martin Vít Matějka2, Jindřich Fínek2
1 Klinika zobrazovacích metod LF UK a FN, Plzeň
2 Oddělení radoterapie a onkologie FN, Plzeň

Detection of the bone metastases belongs among the important problems of the staging in prostatic, breast and lung carcinoma and also others malignancies. The detection of the increased osteoblastic activity helps to assess the presence of bone metastatic disease including the monitoring of the disease activity. 18F-NaF-PET/CT becomes the alternative method to the bone scintigraphy in patients with suspected or present bone metastases dissemination. Thanks to the physical and physiological behavior, 18F shows the better bio-distribution parameters within the tissues especially in bone compared to 99mTc-methylendifosfonate. The review summarizes the potential of 18F-NaF-PET/CT as an alternative method to bone scintigraphy.

Keywords: 18F-NaF, 18F-NaF-PET/CT, bone scintigraphy, bone metastases, prostatic carcinoma

Accepted: January 15, 2011; Published: March 1, 2011  Show citation

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Ferdová E, Ferda J, Matějka MV, Fínek J. Imaging of the bone metastase with 18F-NaF-PET/CT. Ces radiol. 2011;65(1):51-60.
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