Ces radiol. 2021, 75(1):72-76 | DOI: 10.55095/CesRadiol2021/009

Aplication of Gay-Dutka/Vašaková method and its modifications in assesment of extend of lung intersticial dissease associated with scleroderma on a chest CT (pilot study)Original article

Jiří Vaňásek1, Pavel Eliáš1, Tomáš Soukup2, Martin Hyršl1, Eva Čermáková3, Eva Kočová1
1 Radiologická klinika LF UK a FN, Hradec Králové
2 Subkatedra revmatologie, 2. interní gastroenterologická klinika LF UK a FN, Hradec Králové
3 Ústav lékařské biofyziky LF UK, Hradec Králové

Aim: The aim of this study is to asses the suitability of three different ways how to quantify systemic sclerosis associated interstitial lung disease (SSc-ILD).

Methods: In a group of 23 patients who met classification criteria for systemic sclerosis (SSc) the extent of pulmonary interstitial involvement in HRCT of the chest was evaluated by three different approaches. The essential method is a modified methodology according to Gay-Dutka/Vašáková, further we worked with its two simplifications. The first is the quantification of SSc-ILD in percent in a few cross-sectional levels the second is the determination of the percentage of changes in the most affected level. The results were compared with the development of selected indicators of pulmonary functional tests over the time.

Results: There was not found statistically significant relationship between SSc-ILD quantification procedures and pulmonary function development over the time (p = 0.07), Nevertheless in subanalysis was found a trend towards relationship between lung function evolvement and percentage of changes in more levels or eventually Gay-Dutka/Vašáková method. Both methods have relatively high sensitivity towards the prediction of lung tets worsening. 85.7% is senzitivity of change percetage in more levels.

Conclusion: Even though the results are not statistically significant, as the most suitable approach for quantification of SSc-ILD seems to be the percentual expression in more levels that is because of the trend that was found. Gathering of data continues and in a larger group of subjects the relationship can be statistically significant.

Keywords: HRCT, interstitium, lung, quantification, systemic sclerosis
Grants and funding:

Podpořeno SVV 260398/2020 Charles University research projects [PROGRES Q40-15.

Accepted: January 31, 2021; Published: March 1, 2021  Show citation

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Vaňásek J, Eliáš P, Soukup T, Hyršl M, Čermáková E, Kočová E. Aplication of Gay-Dutka/Vašaková method and its modifications in assesment of extend of lung intersticial dissease associated with scleroderma on a chest CT (pilot study). Ces radiol. 2021;75(1):72-76. doi: 10.55095/CesRadiol2021/009.
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