Ces radiol. 2023, 77(3):140-143 | DOI: 10.55095/CesRadiol2023/016

Lung inflammatory pseudotumor mimicking malignancy on hybrid FDG PET/CT imaging - a case reportCase report

Jiří Doležal1, Jiří Vaňásek2, Martina Beránková1, Leona Studničková1, Lucie Turková2, Michal Hrnčiarik3, Helena Hornychová4, Ivo Hanke5
1 Oddělení nukleární medicíny LF UK a FN, Hradec Králové
2 Radiologická klinika LF UK a FN, Hradec Králové
3 Plicní klinika LF UK a FN, Hradec Králové
4 Fingerlandův ústav patologie LF UK a FN, Hradec Králové
5 Kardiochirurgická klinika LF UK a FN, Hradec Králové

Aim: To present an interesting case of inflammatory pseudotumour in the rightlung simulating a malignant epithelial tumour with locoregional disseminationon 18F-FDG PET/CT in a 63-year-old woman.

Method: The patient was treated for asthma bronchiale for a long time. Thechest X-ray and CT scan showed a new soft tissue expansion in the right lunghilum, which was highly suspicious for a tumour. An 18F-FDG PET/CT imaging wasperformed to complete staging before surgical intervention. A whole-bodyPET/CT scan was performed from the base of the skull to the mid-thighs 60minutes after intravenous administration of 18F-FDG with an activity of 416MBq (5.1 MBq/kg). The acquisition time of PET imaging was 2.5 minutes per bedprojection and a total of 7 bed projections were performed. Native CT imagingwas performed in an identical range.

Results: PET/CT showed intense 18F-FDG uptake in tumorous expansion in theright lung hilum and in mediastinal lymph nodes. The finding was evaluated asa viable tumour expansion in the right lung hilum with viable tumorlymphadenopathy in the mediastinum. This was followed by a right-sidedmid-lung lobectomy and mediastinal lymphadenectomy. However, histologicalexamination excluded malignant epithelial tumor structures in the resectedlung lobe and lymph nodes; an inflammatory pseudotumour was proven.

Conclusion: 18F-FDG PET/CT imaging showed an inflammatory pseudotumour in theright lung simulating a malignant epithelial tumour with dissemination to themediastinal lymph nodes.

Keywords: inflammatory pseudotumor, lung, 18F-FDG, PET/CT

Published: September 1, 2023  Show citation

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Doležal J, Vaňásek J, Beránková M, Studničková L, Turková L, Hrnčiarik M, et al.. Lung inflammatory pseudotumor mimicking malignancy on hybrid FDG PET/CT imaging - a case report. Ces radiol. 2023;77(3):140-143. doi: 10.55095/CesRadiol2023/016.
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    References

    1. Ziessman HA, O'Malley J, Thrall JH. Nuclear Medicine - The Requisites in Radiology, Third Edition. Philadelphia, USA: Elsevier Mosby 2006; 302-305.
    2. Liu Ch, Ma Ch, Duan J, Qiu Q, Guo Y, Zhang Z, Yin Y. Using CT texture analysis to differentiate between peripheral lung cancer and pulmonary inflammatory pseudotumor. BMC Medical Imaging 2020; 20(1): 75-85. Go to original source... Go to PubMed...
    3. Patnana M, Sevrukov BA, Elsayes KM, Viswanathan Ch, Lubner M. Inflammatory pseudotumor: The great mimicker. AJR Am J Roentgenol 2012; 198(3): 17-27. Go to original source... Go to PubMed...
    4. Klímová A, Diblík P, Kuthan P, Sklenka P. Zánětlivý pseudotumor očnice. Neurologie pro Praxi 2011; 12(3): 164-166.
    5. Narla DL, Newman B, Spottswood SS, Marla S, Kolli R. Inflammatory pseudotumor. Radiographics 2003; 23(3): 719-729. Go to original source... Go to PubMed...
    6. Kaplan J, Mangum C, Shoukry M, Gabriel E. Inflammatory pseudotumor resembling a malignant pancreatic disease process. Anticancer Res 2021; 41(4): 2079-2082. Go to original source... Go to PubMed...
    7. Hirai S, Katayama T, Chatani N, Satoh K, Mitsui N. Inflammatory Pseudotumor Suspected of Lung Cancer Treated by Thoracoscopic Resection. Ann Thorac Cardiovasc Surg 2011; 17(1): 48-52. Go to original source... Go to PubMed...
    8. Sulu E, Damadoglu E, Takir HB, Okur HK, Köroglu E, Yilmaz A. A case of endobronchial inflammatory pseudotumor invading the mediastinum. Tuberk Toraks 2011; 59(1): 77-80. Go to original source... Go to PubMed...
    9. Yano Y, Mori M, Kagami S, Fushitani K., Sugano T, Namba Y, Yoneda T, Yokota S, Maeda H, Ueda K. Inflammatory pseudotumor of the lung with rapid growth. Intern Med 2009; 48(15): 1279-1282. Go to original source... Go to PubMed...
    10. Dacic S, Lazar AJ, Noguchi M, Maleszewski JJ. (eds.); Tavora F, Hornick JL, Jain D, et al. (authors) Inflammatory myofibroblastic tumour of the thorax. In: WHO Classification of Tumours Editorial Board. Thoracic tumours. Lyon (France): International Agency for Research on Cancer; 2021 (WHO classification of tumours series, 5th ed.; vol. 5). https://publications.iarc.fr/595
    11. Yi E, Aubry MCh. Pulmonary pseudoneoplasms. Arch Pathol Lab Med 2010; 134(3): 417-426. Go to original source... Go to PubMed...

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