Ces radiol. 2007, 61(1):80-84

Radiation dose to the hands of nuclear medicine staff preparing radiopharmaceuticals with gamma emitters including positron radionuclide 18FReview article

Václav Husák1,2, Jaroslav Ptáček2, Jarmila Drymlová1, Z. Pásková3
1 Klinika nukleární medicíny LF UP a FN, Olomouc
2 Oddělení lékařské fyziky a radiační ochrany FN, Olomouc
3 Státní úřad pro jadernou bezpečnost, Praha

Review of literature dealing with radiation dose to the hands of radiopharmaceutical staff published from 1975 till 2006 is discussed. Position of thermoluminescence dosimeters is considered either at finger tips (position A) or at the proximal ring finger (position B) during 99Mo-99mTc generators elution, preparation of radiopharmaceuticals, activity measurements and dosing but not during administration to the patients. Personal dose equivalent Hp(0,07) in 1 cm2 is measured in position A, personal dose equivalent for hands in position B. During the preparation of 99mTc, finger tip dose (position A) ranging from 1.2-1.9 mSv/10 GBq without protective devices and from 0.18-1.3 mSv/10 GBq with protective devices was published in the literature between 1975 and 1990. During the manipulation with 18F, finger tip dose (position A) ranged from 0.9-5.8 mSv/10 GBq (mean 3.5 mSv/10 GBq). Between 2000-2005, mean annual hand dose (position B) ranged from 17.5-91 mSv (mean 43.8 mSv) without PET, and from 25-184 mSv (mean 121 mSv) with PET, respectively. Routinely, dose to the hands does not exceed 500 mSv/year. In case of skin dose this is not sure since this parameter is not routinely measured and a risk of superficial contamination exists.

Keywords: radiation dose, nuclear medicine, dosimeters, radiation limits, PET, radiopharmaceuticals

Accepted: July 25, 2006; Published: March 1, 2007  Show citation

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Husák V, Ptáček J, Drymlová J, Pásková Z. Radiation dose to the hands of nuclear medicine staff preparing radiopharmaceuticals with gamma emitters including positron radionuclide 18F. Ces radiol. 2007;61(1):80-84.
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    References

    1. Hušák V, Ptáček J, Mysliveček J. Radiační ochrana pracovníků a obyvatelstva při léčbě radiofarmaky značenými otevřenými zářičem ytriem-90. Čes Radiol 2005; 59: 229-235. Go to original source... Go to PubMed...
    2. Hušák V, Havlík J. Radiační zátěž rukou při práci s generátory 99Mo-99mTc měřená prstovými dozimetry ÚVVR. Jaderná energie 1980; 20: 465-466. Go to original source... Go to PubMed...
    3. Harding LK, Mostafa AB, Thomson WH. Staff radiation doses associated with nuclear medicine procedures. Nucl Med Commun 1990; 11: 271-277. Go to original source... Go to PubMed...
    4. Dhanse S, Martin CJ, Hilditch TE, Elliot AT. A study of doses to the hands during dispensing of radiopharmaceuticals. Nucl Med Commun 2000; 21: 511-519. Go to original source... Go to PubMed...
    5. Jankowski J, Olszewski J, Kluska K. Distribution of equivalent doses to skin of the hands of nuclear medicine personnel. Radiat Prot Dosimetry 2003; 106: 177-180. Go to original source... Go to PubMed...
    6. Berus D, Covens P, Buls N, et al. Extremity doses of workers in nuclear medicine: mapping hand doses in function of manipulation. Congress of IRPA, Madrid 2004 (http://www.irpa11.com).
    7. Whitby M, Martin CJ. A multi-centre study of dispensing methods and hand doses in UK hospital radiopharmacies. Nucl Med Commun 2005; 26: 49-60. Go to original source... Go to PubMed...
    8. Donadille L, El Bouachri A, Lahaye T, et al. Feasibility study of an active extremity dosimetry prototype. Rad Prot Dosimetry 2005; 115: 548-552. Go to original source... Go to PubMed...
    9. Pakbiers MTW, Teule GJJ, Kemerink GJ. Occupational, patient and evironmental radiation dose caused by 18F-FDG PET/CT studies (abstract). Eur J Nucl Med Mol Imaging 2005; 32(Suppl 1): S119.
    10. Guillet B, Quentin P, Waultier S, et al. Technologist radiation exposure in routine clinical practice with 18F-FDG PET. J Nucl Med Technol 2005; 33: 175-179.
    11. Vanhavere F, Berus D, Buls N, Covens P. The use of extremity dosemeters in a hospital environment 2006; 118: 190-195.
    12. Janeba D, Heřmanská J, Bělohlávek O. Personal dosimetry in the PET centre Prague. Nucl Med Review 2000; 3: 189-191.
    13. Chruscielewski W, Olszewski J, Jankowski J, Cygan M. Hand exposure in nuclear medicine workers. Radiat Prot Dosimetry 2002; 101: 229-232. Go to original source... Go to PubMed...
    14. Zito F, Eulisse G, Rozza M. Dosimetric evaluation of workers operating into a PET department. 6th European ALARA Network Workshop, Madrid 2002 (http://ean.cepn.asso.fr).
    15. Hušák V, Ptáček J. Přehled a hodnocení profesionální radiační zátěže a ochranných opatření v nukleární medicíně v České republice v roce 2003. Zpráva pro SÚJB Praha, Olomouc 2005.
    16. Castaldo S. Impact of F-18 on the dose delivered to technologists in a nuclear medicine department (abstract). Nuklearmedizin 2005; 44: A168.
    17. Vyhláška č. 307/2002 Sb., o radiační ochraně, ve znění vyhlášky č. 499/2005 Sb.
    18. Assessment of occupational exposure due to external sources of radiation. Safety Guide No. RS-G-1.3. Vienna: International Atomic Energy Agency 1999. ISBN 92-0-101799-5.
    19. Hušák V, Kleinbauer K, Koranda P. Personnel's skin dose from contamination by radionuclides - approximate simple estimate. XXV. Days of Radiation Protection, Extended Conference Abstracts, Jáchymov 2002, 50-53.
    20. Delacroix D, Guerre JP, Leblanc P, Hickmann C. Radionuclide and radiation protection data handbook 2002. Ashford: Nuclear Technology Publishing 2002. Go to original source...

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