Ces radiol. 2016, 70(1):23-26 | DOI: 10.55095/CesRadiol2016/004
Metastatic melanoma detected by 99mTc-sestamibi SPECT/CT imaging during differentiated thyroid cancer follow-upOriginal article
- Oddělení nukleární medicíny LF UK a FN, Hradec Králové
Aim: To present a rare case report of the metastatic melanoma detected by 99mTc-sestamibi SPECT/CT during differentiated thyroid cancer (DTC) follow-up imaging in a 43-year-old woman.
Method: The patient with positive history of DTC and malignant melanoma after treatment underwent follow-up 99mTc-sestamibi whole body scintigraphy. The additional chest SPECT/CT (single photon emission computed tomography/computed tomography) scan was done in order to improve the three-dimensional view of the axillary region with the increased activity of 99mTc-sestamibi. The multifunctional imaging scanner Infinia and processing system Xeleris (General Electic Healthcare) were used.
Results: The follow-up whole body scintigraphy and chest SPECT/CT revealed unexpected, incidental focal 99mTc-sestamibi uptake in the right axillary lymph node, which was subsequently excised and malignant melanoma metastasis was proven by histopathology.
Conclusion: SPECT/CT is an excellent imaging method facilitating exact spatial location of increased 99mTc-sestamibi in the chest region. The 99mTc-sestamibi SPECT/CT revealed right axillary malignant melanoma metastasis, improved patient management and allowed subsequent successful surgery treatment and changed the patient prognosis.
Keywords: thyroid cancer, melanoma, SPECT/CT, 99mTc-sestamibi
Grants and funding:
Podpořeno MZ ČR - RVO (FNHK, 00179906).
Accepted: February 15, 2016; Published: March 1, 2016 Show citation
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