Ces radiol. 2013, 67(1):39-45

Assessment of Crohn's disease activity with contrast enhanced ultrasoundOriginal article

Jakub Hustý1, Daniel Bartušek1, Vlastimil Válek1, Markéta Smělá$1 Vladimír Zbořil2, Lucie Prokopová2
1 Radiologická klinika FN Brno a Lékařské fakulty Masarykovy univerzity, Brno
2 Interní gastroenterologická klinika FN Brno a Lékařské fakulty Masarykovy univerzity, Brno

Aim: The aim of the study is to asses contribution and possibilities of contrast enhanced ultrasound in assessment of Crohn disease activity.

Method: Sixty one patients underwent colonoscopy (as reference method), native bowel ultrasound examination and contrast enhanced ultrasound examination with further software quantification analysis.

Results: The calculated values of sensitivity/specifity in determining Crohn disease bowel inflammation activity by native ultrasound were 83,3/77,8%. The contrast enhanced ultrasound by using Peak Intensity parametr reached sensitivity/specifity 90,7/83,7%. Statistically significant difference was confirmed also by using subjective evaluation of bowel wall contrast enhancement and quantification parametr Time to Peak.

Conclusion: Contrast enhanced bowel ultrasound proved higher sensitivity and specificity compared to native examination and its use could be contribution in ambiguous or borderline results of native examination.

Keywords: contrast media, Crohn disease, endoscopy ultrasonography

Accepted: January 15, 2013; Published: March 1, 2013  Show citation

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Hustý J, Bartušek D, Válek V, Zbořil MSV, Prokopová L. Assessment of Crohn's disease activity with contrast enhanced ultrasound. Ces radiol. 2013;67(1):39-45.
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