Ces radiol. 2015, 69(2):87-92 | DOI: 10.55095/CesRadiol2015/013

Role of neuroradiologist in the treatment of ischemic strokeReview article

Antonín Krajina, Dagmar Krajíčková
Radiologická klinika a Neurologická klinika LF a FN, Hradec Králové

Recanalization after large vessel occlusion is proven to be a crucial predictor for favorable outcome in acute ischemic stroke. Intravenous thrombolysis with recombinant tissue plazminogen activator (rtPA) has been investigated in several randomized controlled studies and is shown to be a safe and effective treatment. However, efficacy of this therapy is moderate. Mechanical thrombectomy represents further step in the treatment of acute stroke. Several prospective randomized studies proved benefit of the endovascular treatment based on proof of proximal artery occlusion, rapid and effective imaging methods to exclude patients with a large infarct core and efficient workflow to achieve fast recanalization and high recanalization rate. Using the stent-retriever technique proved to be highly technically and clinically effective.

Keywords: ischemic stroke, mechanical thrombectomy, stent-retriever, neurointerventions

Accepted: April 14, 2015; Published: June 1, 2015  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Krajina A, Krajíčková D. Role of neuroradiologist in the treatment of ischemic stroke. Ces radiol. 2015;69(2):87-92. doi: 10.55095/CesRadiol2015/013.
Download citation

References

  1. Péče o pacienty s cerebrovaskulárním onemocněním v České republice. Věstník MZ ČR 2010, částka 2.
  2. Péče o pacienty s akutní cévní mozkovou příhodou. Věstník MZČR 2012, částka 10.
  3. Jauch EC, Saver JL, Adams HP, et al. Guidelines for the early management of patients with acute ischemic stroke. Stroke 2013; 44: 870-947. Go to original source... Go to PubMed...
  4. Skoloudik D, Bar M, Skoda O, et al. Safety and efficacy of the sonographic acceleration of the middle cerebral artery recanalization: results of the pilot thrombotripsy study. Ultrasound Med Biol 2008; 34: 1775-1782. Go to original source... Go to PubMed...
  5. Mikulík R, Bunt LA, Hrdlička D, et al. Calling 911 in response to stroke. A Nationwide Study Assessing Definitive Individual Behavior. Stroke 2008; 39(6): 1844-1849. Go to original source... Go to PubMed...
  6. Bar M, Skoloudik D, Roubec M, et al. Transcranial duplex sonography and CT angiography in acute stroke patiens. J Neuroimaging 2010; 20: 240-245. Go to original source... Go to PubMed...
  7. Roubec M, Kuliha M, Prochazka V, et al. A controlled trial of revascularization in acute stroke. Radiology 2013; 266(3): 871-878. Go to original source... Go to PubMed...
  8. Kuliha M, Roubec T, Jonszta, et al. Safety and efficacy of endovascular sonolysis using the ekosonic endovascular system in patients with acute stroke. Am J Neuroradiol 2013; 34: 1401-1406. Go to original source... Go to PubMed...
  9. Sanak D, Köcher M, Veverka T, et al. Acute combined revascularization in acute ischemic stroke with intracranial arterial occlusion: self-expanding Solitaire stent during intravenous thrombolysis. J Vasc Interv Radiol 2013; 24(9): 1273-1279. Go to original source... Go to PubMed...
  10. Barber PA, Dechmuk AM, Zhang J. Buchan AM. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. Lancet 2000; 355: 1670-1674. Go to original source... Go to PubMed...
  11. Sarraj A, Albright K, Barreto AD, et al. Optimizing prediction scores for poor outcome after intra-arterial therapy in anterior circulation acute ischemic stroke. Stroke 2013; 44: 3324-3330. Go to original source... Go to PubMed...
  12. Strbian D, Meretoja A, Ahlhelm FJ, et al. Predicting outcome of IV thrombolysis-treated ischemic stroke patients. Neurology 2012; 78: 427-432. Go to original source... Go to PubMed...
  13. Berkhemer OA, Fransen PSS, Beumer D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015; 372(1): 11-20. Go to original source... Go to PubMed...
  14. Cooray C, Fekete K, Mikulik R, et al. Threshold for NIH stroke scale in predicting vessel occlusion and functional outcome after stroke thrombolysis. Int J Stroke 2015; v tisku. Go to original source... Go to PubMed...
  15. Heldner MR, Zubler C, Mattle HP, et al. National institutes of health stroke scale score and vessel occlusion in 2152 patients with acute ischemic stroke. Stroke 2013; 44: 1153-1157. Go to original source... Go to PubMed...
  16. Goyal M, Demchuk AM, Menon BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015; 372(11): 1019-1030. Go to original source... Go to PubMed...
  17. Campbell BCV, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015; 372(11): 1009-1018. Go to original source... Go to PubMed...
  18. Mourand I, Machi P, Nogué E, et al. Diffusion-weighted imaging score of the brain stem: a predictor of outcome in acute basilar artery occlusion treated with the Solitaire FR device. Am J Neuroradiol 2014; 35: 1117-1123. Go to original source... Go to PubMed...
  19. Sussman BJ, Fitch TSP, Plainfield NJ. Thrombolysis with fibrinolysin in cerebral arterial occlusion. JAMA 1958; 167: 1705-1709. Go to original source... Go to PubMed...
  20. Chopko BW, Kerber C, Wong W, Georgy B. Transcatheter snare removal of acute middle cerebral artery thromboembolism: technical case report. Neurosurgery 2000; 46: 1529-1531. Go to original source... Go to PubMed...
  21. Krajina A, Krajíčková D, Špriňar Z, et al. Mechanická perkutánní extrakce embolu při akutní cévní mozkové příhodě: kasuistika a přehled literatury. Čes. a slov. Neurol. Neurochir. 2005; 65/101: 51-57.
  22. The NINDS t-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995; 333: 1581-1587. Go to original source... Go to PubMed...
  23. Riedel CH, Zimmermann P, Jensen-Kondering U, et al. The importance of size. Successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length. Stroke 2011; 42: 1775-1777. Go to original source... Go to PubMed...
  24. Meunier JM, Wenker E, Lindsell CHJ, Shaw GJ. Individual lytic efficacy of recombinant tissue plasminogen activator in an in vitro human clot model: rate of "Nonresponse". Acad Emerg Med 2013; 20(5): 449-455. Go to original source... Go to PubMed...
  25. De los Ríos la Rosa F, Khoury J, Kissela BM, et al. Eligibility for intravenous recombinant tissue-type plasminogen activator within a population. The effect of the European Cooperative Acute Stroke Study (ECASS) III trial. Stroke 2012; 43: 1591-1595. Go to original source... Go to PubMed...
  26. Almekhlafi MA, Menon BK, Freiheit EA, et al. A meta-analysis of observational intra-arterial stroke therapy studies using the Merci device, Penumbra system, and retrievable stents. Am J Neuroradiol 2013; 34: 140-145. Go to original source... Go to PubMed...
  27. Smith WS, Sung G, Starkman S, Saver JL, Kidwell CS, Gobin YP, et al. Safety and efficacy of mechanical embolectomy in acute ischemic stroke. Results of the MERCI trial. Stroke 2005; 36: 1432-1440. Go to original source... Go to PubMed...
  28. Krajina A, Krajíčková D, Lojík M, et al. Endovaskulární rekanalizace pří léčba akutních uzávěrů mozkových tepen. Ces Slov Neurol N 2010; 73/106(6): 678-684.
  29. Broderick JP, Palesch YY, Demchuk AM, et al. Endovascular therapy after intravenous t-pa versus t-pa alone for stroke. N Engl J Med 2013; 368: 893-903. Go to original source... Go to PubMed...
  30. Kidwell CS, Jahan R, Saver JL. Endovascular treatment for acute ischemic stroke. N Engl J Med 2013; 368: 2434-2435. Go to original source... Go to PubMed...
  31. Ciccone A, Valvassori L, Nichelatti M, et al. Endovascular treatment for acute ischemic stroke. N Engl J Med 2013; 368: 904-913. Go to original source... Go to PubMed...
  32. Saver JL, Jahan R, Levy EI, et al. Solitaire flow restoration device versus the merci retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial. Lancet 2012; 380: 1241-1249. Go to original source... Go to PubMed...
  33. Nogueira RG, Lutsep HL, Gusta R, et al. Trevo versus merci retrievers for thrombectomy revascularisation of large vessel occlusions in acute ischaemic stroke (TREVO 2): a randomised trial. Lancet 2012; 380: 1231-1240. Go to original source... Go to PubMed...
  34. Sun CHJ, Nogueira RG, Glenn BA, et al. "Picture to puncture" a novel time metric to enhance outcomes in patients transferred for endovascular reperfusion in acute ischemic stroke. Circulation 2013; 127: 1139-1148. Go to original source... Go to PubMed...
  35. Menon BK, d'Esterre CD, Qazi EM, et al. Multiphase CT angiography: a new tool for the imaging triage of patients with acute ischemic stroke. Radiology 2015; 275: 510-520. Go to original source... Go to PubMed...
  36. Vagal AS, Khatri P, Broderick JP, et al. Time to angiographic reperfusion in acute ischemic stroke: decision analysis. Stroke 2014; 45: 3625-3630. Go to original source... Go to PubMed...
  37. Khatri P, Yeatts SD, Mazighi M, et al. Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the Interventional Management of Stroke (IMS III) phase trial. Lancet Neurol 2014; 13: 567-574. Go to original source... Go to PubMed...
  38. Almekhlafi MA, Davalos A, Bonafe A, et al. Impact of age and baseline NIHSS scores on clinical outcome in the mechanical thrombectomy using Solitaire FR in acute ischemic stroke study. Am J Neuroradiol 2014; 35: 1337-1340. Go to original source... Go to PubMed...
  39. Kappelhof M, Marquering HA, Berkhemer OA, Majoie CB. Intra-arterial treatment of patients with acute ischemic stroke and internal carotid artery occlusion: a literature review. J Neurointerv Surg 2015; 7(1): 8-15. Go to original source... Go to PubMed...
  40. Cohen JE, Gomori JM, Rajz G, et al. Extracranial carotid artery stenting followed by intracranial stent-based thrombectomy for acute tandem occlusive disease. J Neurointerv Surg 2014; v tisku. Go to original source... Go to PubMed...
  41. Maurer CJ, Joachimski F, Berlis A. Two in one: endovascular treatment of acute tandem occlusions in the anterior circulation. Clin Neuroradiol 2014; v tisku. Go to original source...
  42. Lescher S, Czeppan K, Porto L, Singer OC, Berkefeld J. Acute stroke and obstruction of the extracranial carotid artery combined with intracranial tandem occlusion: results of interventional revascularization. Cardiovasc Intervent Radiol 2015; 38: 304-313. Go to original source... Go to PubMed...
  43. Dababneh H, Bashir A, Hussain M, et al. Endovascular treatment of tandem internal carotid and middle cerebral artery occlusions. J Vasc Interv Neurol 2014; 7(4): 26-31.
  44. Stampfl S, Ringleb PA, Möhlenbruch M, et al. Emergency cervical internal carotid artery stenting in combination with intracranial thrombectomy in acute stroke. Am J Neuroradiol 2014; 35: 741-746. Go to original source... Go to PubMed...
  45. Schonewille WJ, Wijman CHA, Michel P, et al. Treatment and outcomes of acute basilar artery occlusion in the basilar artery international cooperation study (BASICS): a prospective registry study. Lancet Neurol 2009; 8: 724-730. Go to original source... Go to PubMed...
  46. Kumar G, Shahripour RB, Alexandrov AV. Recanalization of acute basilar artery occlusion improves outcomes: a meta-analysis. J Neurointervent Surg 2014; v tisku. Go to original source...
  47. Danière F, Lobotesis K, Machi P, et al. Patient selection for stroke endovascular therapy - DWI-ASPECT thresholds should vary among age groups: insights from the RECOST study. Am J Neuroradiol 2015; 36: 32-39. Go to original source... Go to PubMed...
  48. Hakimelahi R, Vachta BA, Copen WA, et al. Time and diffusion lesion size in major anterior circulation ischemic strokes. Stroke 2014; 45(10): 2936-2941. Go to original source... Go to PubMed...
  49. Emberson J, Lees KR, Lyden P, et al. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 2014; 384: 1929-1935. Go to original source... Go to PubMed...
  50. Mordasini P, El-Koussy M, Brekenfeld C, et al. Applicability of tableside flat panel detector CT parenchymal cerebral blood volume measurement in neurovascular interventions: preliminary clinical experience. Am J Neuroradiol 2012; 33(1): 154-158. Go to original source... Go to PubMed...
  51. Neumann J, Tomek A, Školoudík D, et al. Doporučený postup pro intravenózní trombolýzu v léčbě akutního mozkového infarktu - verze 2014. Ces Slov Neurol N 2014; 77/110(3): 381-385.
  52. Manning NW, Campbell BCV, Oxley TJ, Chapot R. Acute ischemic stroke. Time, penumbra, and reperfusion. Stroke 2014; 45: 640-644. Go to original source... Go to PubMed...
  53. Turk AS, Spiotta A, Frei D, et al. Initial clinical experience with the ADAPT technique: A direct aspiration first pass technique for stroke thrombectomy. J Neurointerv Surg 2014; 6(3): 231-237. Go to original source... Go to PubMed...
  54. Power S, Matouk CH, Casaubon LK, et al. Vessel wall magnetic resonance imaging in acute ischemic stroke. Effects of embolism and mechanical thrombectomy on the arterial wall. Stroke 2014; 45: 2330-2334. Go to original source... Go to PubMed...
  55. Nikoubashman O, Reich A, Pjontek R, Jungbluth M, Wiesmann M. Postinterventional subarachnoid haemorrhage after endovascular stroke treatment with stent retrievers. Neuroradiology 2014; 56: 1087-1096. Go to original source... Go to PubMed...
  56. Behme D, Gondecki L, Fiethen S, et al. Complications of mechanical thrombectomy for acute ischemic stroke - a retrospective single-center study of 176 consecutive cases. Neuroradiology 2014; 56: 467-476. Go to original source... Go to PubMed...
  57. Kalvach P. Mozkové ischémie a hemoragie. Praha: Grada Publishing 1997.
  58. Friedrich B, Gawlitza M, Schob S, et al. Distance to thrombus in acute middle cerebral artery occlusion. A predictor of outcome after intravenous thrombolysis for acute ischemic stroke. Stroke 2015; 46: 692-696. Go to original source... Go to PubMed...
  59. Talke PO, Sharma D, Heyer EJ, et al. Society for neuroscience in anesthesiology and critical care expert consensus statement: anesthetic management of endovascular treatment for acute ischemic stroke. Stroke 2014; 45: e138-150. Go to original source... Go to PubMed...

This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.