Ces radiol. 2019, 73(4):256-262 | DOI: 10.55095/CesRadiol2019/039
Cardiac metastasis in a patient with breast cancerCase report
- 1 Oddělení radiologie, Masarykův onkologický ústav, Brno
- 2 Klinika komplexní onkologické péče, Masarykův onkologický ústav, Brno
- 3 Klinika radiologie a nukleární medicíny FN, Brno-Bohunice
- 4 Lékařská fakulta MU, Brno
- 5 Klinika zobrazovacích metod FN U sv. Anny, Brno
In the Czech Republic, breast cancer is one of the most common oncological diseases in women, mainly metastasizing to bones, lungs, brain and liver. Cardiac metastases are a known, but infrequent, complication of an advanced disease. The spread of a malignant disease to the heart and pericardium usually occurs through the lymphatic system. Breast cancer is among the most common tumors metastasizing to this area. Although heart and pericardial metastases are generally rare, they are much more frequent than primary tumors and are associated with poor prognosis. They are mostly clinically silent and therefore under-diagnosed. The diagnostic method of choice is echocardiography, however, cardiac infiltration can sometimes be suspected from posteroanterior chest x-ray. More detailed evaluation is offered by CT and MRI imaging. We are presenting the case of 69-year-old female with advanced breast cancer and metastatic right atrial infiltration incidentally found during CT scan of chest and abdomen.
Keywords: breast cancer, cardiac metastases, right atrial thrombus
Accepted: November 15, 2019; Published: December 1, 2019 Show citation
References
- Butany J, Nair V, Naseemuddin A, Nair GM, Catton C, Yau T. Cardiac tumours: diagnosis and management. Lancet Oncol 2005; 6(4): 219-228.
Go to original source...
Go to PubMed...
- Bussani R, De-Giorgio F, Abbate A, Silvestri F. Cardiac metastases. J Clin Pathol 2007; 60(1): 27-34.
Go to original source...
Go to PubMed...
- Lichtenberger JP, Reynolds DA, Keung J, et al. Metastasis to the heart: A radiologic approach to diagnosis with pathologic correlation. Am J Roentgenol 2016; 207: 764-772.
Go to original source...
Go to PubMed...
- Goldberg AD., Blankstein R, Padera RF. Tumors metastatic to the heart. 2013; 128(16): 1790-1794.
- Yusuf SW, Bathina JD, Qureshi S, et al. Cardiac tumors in a tertiary care cancer hospital: clinical features, echocardiographic findings, treatment and outcomes. Heart Int 2012; 7(1): e4.
Go to original source...
Go to PubMed...
- Cates CU, Virmani R, Vaughn WK, Robertson RM. Electrocardiographic markers of cardiac metastasis. Am Heart J 1986; 112(6): 1297-1303.
Go to original source...
Go to PubMed...
- Lam KY, Dickens P, Chan AC. Tumors of the heart. A 20-year experience with a review of 12,485 consecutive autopsies. Arch Pathol Lab Med 1993; 117(10): 1027-1031.
- Hancock EW. Neoplastic pericardial disease. Cardiol Clin 1990; 8(4): 673-682.
Go to original source...
- Weiss L. An analysis of the incidence of myocardial metastasis from solid cancers. Br Heart J 1992; 68(5): 501-504. doi: 10.1136/hrt.68.11.501
Go to original source...
Go to PubMed...
- Petersen CD, Robinson WA, Kurnick JE. Involvement of the heart and pericardium in the malignant lymphomas. Am J Med Sci 1976; 272(2): 161-165.
Go to original source...
Go to PubMed...
- Schoen FJ, Berger BM, Guerina NG. Cardiac effects of noncardiac neoplasms. Cardiol Clin 1984; 2(4): 657-670.
Go to original source...
- Mukai K, Shinkai T, Tominaga K, et al. The incidence of secondary tumors of the heart and pericardium: a 10-year study. Jpn J Clin Oncol 1988; 18(3): 195-201.
- Tesolin M, Lapierre C, Oligny L, Bigras J-L, Champagne M. Cardiac Metastases from Melanoma. RadioGraphics 2005; 25(1): 249-253.
Go to original source...
Go to PubMed...
- Rahbar K, Seifarth H, Schäfers M, Stegger L, Hoffmeier A, Spieker T, et al. Differentiation of malignant and benign cardiac tumors using 18F-FDG PET/CT. J Nucl Med 2012; 53(6): 856-863.
Go to original source...
Go to PubMed...
- Nensa F, Tezgah E, Poeppel TD, Jensen CJ, Schelhorn J, Köhler J, et al. Integrated 18F-FDG PET/MR imaging in the assessment of cardiac masses: a pilot study. J Nucl Med 2015; 56(2): 255-260.
Go to original source...
Go to PubMed...
- Bruce CJ. Cardiac tumours: diagnosis and management. Heart 2011; 97(2): 151-160.
Go to original source...
Go to PubMed...
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