Ces radiol. 2009, 63(1):42-47

Evaluation of dynamics of the bowel wall perfusion in the assessment of Crohn's disease activity: comparison of ultrasonography and magnetic resonance imaging with blood-pool contrast agentOriginal article

Hynek Mírka1, Jiří Ferda1, Kristýna Ohlídalová1, Jana Koželuhová2
1 Radiodiagnostická klinika LF UK a FN, Plzeň
2 I. interní klinika LF UK a FN, Plzeň

Aim: To determine the utility of the bowel wall perfusion dynamics evaluation using ultrasonography and magnetic resonance with blood-pool contrast agent; to assess the role in the assessment of Crohn's disease activity and to compare both methods.

Method: 15 patients with Crohn's disease underwent both ultrasonographic and magnetic resonance examination with blood-pool contrast agent. Time to maximal bowel wall enhancement was established and results of both methods were correlated with clinical and laboratory finding.

Results: Average time to maximal bowel wall enhancement detected by ultrasonography was 8.3 s in active Crohn's disease and 14.7 s in remission (p = 0.0011). In magnetic resonance was time to maximal enhancement 18.6 s for active disease and 29.4 s for remission (p = 0.0149). Ultrasonography established disease activity correctly in 87% of patients and magnetic resonance in 93%. Agreement of both imaging methods was reached in 93% of cases.

Conclusion: Results of this limited study indicate, that assessment of the bowel wall enhancement dinamics using ultrasonography and magnetic resonance with blood-pool contrast agent may be used to determine Crohn's disease actvity.

Keywords: Crohn's disease, bowel wall perfusion, ultrasonography, magnetic resonance imaging, blood-pool contrast agent
Grants and funding:

Práce byla podpořena výzkumným záměrem MSM-0021620819.

Accepted: February 1, 2009; Published: March 1, 2009  Show citation

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Mírka H, Ferda J, Ohlídalová K, Koželuhová J. Evaluation of dynamics of the bowel wall perfusion in the assessment of Crohn's disease activity: comparison of ultrasonography and magnetic resonance imaging with blood-pool contrast agent. Ces radiol. 2009;63(1):42-47.
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