Ces radiol. 2011, 65(1):14-18

Verbal working memory investigation using functional MRIOriginal article

Zbyněk Tüdös1, Petr Hluštík2, Pavel Hok2
1 Radiologická klinika UP a FN, Olomouc
2 Neurologická klinika UP a FN, Olomouc

Aim: To perform functional MRI in a group of healthy volunteers using working memory task to obtain the physiological activation pattern.

Method: We performed functional MRI in 20 healthy right-handed volunteers (10 men and 10 women) to assess their verbal working memory with Item Recognition Task using 1.5T scanner. The task used block design. Single-subject and group fMRI analyses were performed using the FEAT software from FSL library.

Results: The task activated mainly frontal lobes and regions of basal ganglia with left-sided dominance. Speech-related areas of temporal lobes and hippocampi were also recruited. Activations in the parietal lobes were less pronounced. Cerebellum was strongly activated.

Conclusion: We obtained normative data for subsequent examination of patient with working memory impairment.

Keywords: fMRI, verbal working memory, brain mapping
Grants and funding:

Studie vznikla za finanční podpory vnitřního projektu Lékařské fakulty Univerzity Palackého v Olomouci č. 91110241.

Accepted: December 20, 2010; Published: March 1, 2011  Show citation

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Tüdös Z, Hluštík P, Hok P. Verbal working memory investigation using functional MRI. Ces radiol. 2011;65(1):14-18.
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