Ces radiol. 2007, 61(4):438-441
Causes of positive 99mTc-pertechnetate uptake during scintigraphy detection of ectopic gastric mucosaOriginal article
- Oddělení nukleární medicíny LF UK a FN, Hradec Králové
Aim and Background. To present four cases of positive uptake of 99mTc-pertechnetate during Meckel's diverticulum scintigraphy in patients with lower gastrointestinal bleeding. Gastric mucosa may be presented in Meckel's diverticulum and associated with peptic ulcer disease and lower gastrointestinal (GI) bleeding. 99mTc-pertechnetate scintigraphy can help establish diagnosis of ectopic gastric mucosa.
Method: One hundred patients (22 adults and 78 children) underwent 99mTc-pertechnetate scintigraphy from 1994 to 2006. All patients had recent history of bleeding into the lower GI tract from unexplained source (melaena, haematochezia). In all patients, imaging studies and endoscopy did not reveal the source of bleeding. Dynamic and static scintigraphy of the abdomen was performed. If necessary, SPECT was added to improve sensitivity, specificity and better spatial resolution.
Results: Four patients (three children and one adult) had positive scintigraphy. Patients underwent surgery and Meckel's diverticulum with ectopic gastric mucosa was confirmed histologically. There were four cases of positive 99mTc-pertechnetate uptake: large bowel irritation after colonoscopy with hyperemia and capillary leak, accumulation in renal pelvis, renal graft with 99mTc-pertechnetate uptake in the right iliac fossa, and hyperaemia with increased blood pool of young female uterus.
Keywords: ectopic gastric mucosa, positive and negative studies, gastrointestinal bleeding, Meckel's diverticulum scintigraphy
Accepted: February 15, 2007; Published: December 1, 2007 Show citation
References
- Thrall JH, Ziessman HA. Nuclear Medicine - The requisites, 2nd edition. Mosby, Inc. A Harcourt Health Sciences Company St. Louis, Missouri 2001.
- Benson CB. Surgical implications of Meckel's diverticulum. In: Mustard W., Ravitch M, et al., Pediatric Surgery, Chicago, Year Book Medical Publishers 1969.
- Sedláčková M, et al. Předoperační diagnostika krvácejícího Meckelova divertiklu pomocí radioaktivního 99mTc-technecystanu. Čs. Gastroent 1980; 34(7): 460-464.
- Ford PV, Bartold SP, et al. Procedure Guideline for Gastrointestinal Bleeding and Meckel's Diverticulum Scintigraphy. J Nucl Med 1999; 40(7): 1226-1232.
- Siddiqui A, Ryo UY, et al. Arteriovenous malformation simulating Meckel's diverticulum on 99mTc-pertechnetate abdominal scintigraphy. Radiology 1977; 122: 173.
Go to original source... 
Go to PubMed... - Beylergil V, Kiratli PO. False impression of positive Meckel's scintigraphy caused by ectopic cross-fused kidneys. Clin Nucl Med 2001; 26: 894-895. Go to original source... Go to PubMed...
- Delbeke D., Frexes-Steed M. The "fading" Meckel's divertikulum. An unusual scintigraphic presentation. Clin Nucl Med 1992; 17: 701-704. Go to original source... Go to PubMed...
- Adams BK, Abudia A et al. A moving Meckel's diverticulum on Tc-99m pertechnetate imaging in a patient with lower gastrointestinal bleeding. Clin Nucl Med 2003;2 8(11): 908-910. Go to original source... Go to PubMed...
- Young TH, Shyu RY, et al. Visualisation of a photopenic lesion secondary to a giant small bowel diverticulum with fecal retention during Meckel's scintigraphy. Clin Nucl Med 1998; 23(12): 857-858. Go to original source... Go to PubMed...
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