Ces radiol. 2010, 64(1):61-63
Detection of the cold lesion vertebral hemangioma by means of 99mTc-nanocolloid bone marrow scintigraphyOriginal article
- 1 Oddělení nukleární medicíny FN, Hradec Králové
- 2 Radiologická klinika FN, Hradec Králové
Aim: To present a case report of the detection of the cold lesion vertebral hemangioma by means of the bone marrow scintigraphy with 99mTc labelled nanocolloid in woman with carcinoma cervicis uteri.
Method: 68-years-old woman with carcinoma cervicis uteri (T2b, N1, M0) underwent the bone marrow scintigraphy with 99mTc labelled nanocolloid for assessment of the red bone marrow range before IMRT pelvis radiotherapy. The applied activity of the 99mTc-nanocolloid was 440 MBq. The whole body scintigraphy (anterior and posterior views) was started 45 minutes after intravenous injection of the radiotracer. The static spine scintigraphy with zoom two was added to improve sensitivity. The rotating, digital, double-head gamma camera VariCam (Elscint) with infrared body contouring and large field of view was used. Gamma camera was fitted with low-energy, high resolution, parallel-hole collimators. Images were evaluated by conventional processing system Xpert-Pro (Elscint).
Results: The bone marrow whole body scintigraphy with 99mTc-nanocolloid demonstrated the large photopenic, cold lesion was in body vertebra L4, reported as bone marrow metastasis. Subsequent L, S spine x-ray and whole body bone scintigraphy with 99mTc-MDP were normal. CT scan confirmed the presence of vertebral hemangioma.
Conclusion: Photopenic, cold lesion in the benign vertebral hemangioma should be considered metastasis on bone marrow whole body scintigraphy and could have made difficulties in the differential diagnosis of the focal cold lesion.
Keywords: cold lesion, vertebral hemangioma, bone marrow scintigraphy, 99mTc-nanocolloid
Accepted: December 20, 2009; Published: March 1, 2010 Show citation
References
- Sander MP, Coleman RE, Patron JA, Wackers FJTh, Gottschalk A. Diagnostic Nuclear Medicine. Fourth Edition. Philadelphia: Lippincott Williams & Wilkins 2003; 565-587.
- Hušák V, Petrová K, Masopust J, Mysliveček M. Aplikované aktivity radiofarmak, radiační zátěž a radiační riziko vyšetřovacích postupů v nukleární medicíně. Čas Lék čes 1999; 138(11): 323-328.
Go to original source... 
Go to PubMed... - Makhija M, Bofill ER. Hemangioma, a rare cause of photopenic lesion on skeletal imaging. Clin Nucl Med 1988; 13(9): 661-662. Go to original source... Go to PubMed...
- Demizu Y, Zamyji S, Takada Y. Vertebral hemangioma demostrated by Tc-99m-DTPA-human serum albumin SPECT. Clin Nucl Med 2002; 27(2): 126-127. Go to original source... Go to PubMed...
- Giacomuzzi F, Di Gregorio F, Capobianco D, De Cristofaro M, Moretti CA, Guerra UP. Cold lesion of a vertebral angioma with Tc-99m-labeled monoclonal antibodies against granulocytes. Clin Nucl Med 1999; 24(11): 864-867. Go to original source... Go to PubMed...
- Dillman JR, Brown RK, Frey KA, Quint DJ. Vertebral body hemangioma visualized on Tc-99m HMPAO-labeled leukocyte SPECT/CT. Clin Nucl Med 2008; 33(8): 587-590. Go to original source... Go to PubMed...
- Khan S, Dunn J, Strickland N, Al-Nahhas A. Iodine-123 uptake in vertebral haemangiomas in a patient with papillary thyroid carcinoma. Nucl Med Rev Cent East Eur 2008; 11(1): 30-33.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.