Ces radiol. 2013, 67(3):209-213

Utilizing magnetic resonance imaging in prenatal detection of cleft lip and palate cleftsOriginal article

Zdeněk Bělobrádek¹, Jan Žižka¹, Ludovít Klzo¹, Eva Šimáková², Karel Hodík³, Eva Čermáková⁴, Pavel Eliáš¹

¹ Radiologická klinika LF UK a FN, Hradec Králové

² Fingerlandův ústav patologie FN, Hradec Králové

³ Porodnická a gynekologická klinika LF UK a FN, Hradec Králové

⁴ Oddělení výpočetní techniky LF UK, Hradec Králové

Aim: Assessing accurancy and credibility of MRI in the assessment of fetal facial cleft lip defects severity using interpretive agreement study between several specialists.

Methods: Our study consists of 23 MRI examinations of fetusee in gestation age before 24 week with differently severe lip clefts, which were detected by ultrasound as well as other 17 examinations without face anomaly (whole group counts 40 cases). Datasets were anonymized and analyzed by 3 radiologists and statistical analysis was performed. According to standardised protocol presence of cleft and degree of severity was evalueted - alveolar ridge envolment, continuation or noncontinuation to pallate.
The examinations were perfomed by Siemens Magnetom Symfony Masestro Class 1.5 T with use of array coils.

Results: The best degree of interpretive agreement was in evaluation of alveolar ridge envolment - 94% (generalized kappa 0,894, SE 0,106), for isolated cleft lip it was 90% (generalized kappa 0,848, SE 0,083) and for defect of palatte 86% (generalized kappa 0,711, SE 0,119).

Conclusion: MRI examination could be successfully used for more accurate imaging of cheilognathopalattoschisis of fetuses within the 24 gestation week of gravidity. The best credibility is for alveolar ridge defect detection, and this information is clinical very valuable.

Keywords: antenatal MR, cleft lip, cleft palatte, alveolar ridge

Accepted: March 15, 2013; Published: September 1, 2013  Show citation