Ces radiol. 2008, 62(1):97-102

Intracranial dural sinus thrombosis, a case reportCase report

Ivana Vachaľová¹, Viliam Porubec¹, Anna Remková², Miroslav Satko³, Vladimír Javorka⁴, Jozef Bilický⁴

¹ Neurologická klinika LF UK a FNsP, Nemocnica Staré Mesto, Bratislava

² Interná klinika LF UK a FNsP, Bratislava

³ Pracovisko magnetickej rezonancie, Dr. MAGNET spol. s r.o., Bratislava

⁴ Rádiodiagnostická klinika LF UK a FNsP, Nemocnica Staré Mesto, Bratislava

Intracranial dural sinus thrombosis is a relative uncommon vascular disorder, with various aetiology but a common pathophysiologic pathway which results from imbalanced procoagulation and anticoagulation blood factors equilibrium, leading to the acceleration of mechanisms resulting in thrombophilia.
We present an unusual case of a woman who completely recovered clinically and where the course of the disease was accompanied by some peculiarities in aetiology, clinical symptoms, and radiologic findings.
The condition started with atypically rapid onset, without any remarkable prodromes, suggesting a subarachnoidal haemorrhage. The exact aetiology of the thrombophilic condition in our patient is still not elucidated, despite all available laboratory test results. We suppose that it could be a rare case of cryptogenic primary thrombophilia which presented without any previous manifestations of venous thrombembolic disease. The use of hormonal contraceptives together with nicotinism might have led to acquired thrombophilic state, too. Resistance to peroral anticoagulation therapy was observed. Radiological findings corresponded well with development of clinical condition. Currently, the patient's dural venous sinuses are completely recanalised.

Keywords: empty delta sign, cryptogenic thrombophilic state, magnetic resonance angiography, cerebral venous sinus thrombosis

Accepted: January 20, 2008; Published: March 1, 2008  Show citation