Ces radiol. 2018, 72(4):228-236 | DOI: 10.55095/CesRadiol2018/031
CT findings in lung adenocarcinhoma with lepidic growthPicture essay
- 1 Klinika zobrazovacích metod LF UK a FN, Plzeň
- 2 Biomedicínské centrum lékařské fakulty UK, Plzeň
- 3 Klinika pneumologie a ftizeologie LF UK a FN, Plzeň
- 4 Chirurgická klinika LF UK a FN, Plzeň
- 5 Šiklův ústav patologie LF UK a FN, Plzeň
Adenocarcinoma with lepidic growth is a variant of lung adenocarcinoma, which, if early detected, is a very good prognosis. In non-invasive and minimally invasive variants that have a 100% 5-year survival in the case of radical treatment, we often find a nodule with ground glass opacity. In more advanced stages, images are more variable and they be may be confused with non-tumorous diseases. The pictorial essay gives an overview of CT findings in adenocarcinomas with lepidic growth. There is also briefly mentioned issue of diagnostics using positron emission tomography.
Keywords: lung, adenocarcinoma with lepidic growth, computed tomography, positron emission tomography
Grants and funding:
Podpořeno projektem Ministerstva zdravotnictví ČR Koncepční rozvoj výzkumné instituce 00669806 - FN Plzeň, projektem Univerzity Karlovy v Praze Progress Q39 a projektem CZ.1.05/2.1.00/03.0076 Evropského fondu pro regionální rozvoj.
Accepted: December 15, 2018; Published: December 1, 2018 Show citation
References
- Travis WD, Brambilla E, Noguchi M, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma. J Thorac Oncol 2011; 6: 244-285.
Go to original source... 
Go to PubMed... - Travis WD, Brambilla E, Nicholson AG, et al. The 2015 World Health Organization Classification of Lung Tumors. Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification. J Thorac Oncol 2015; 10: 1243-1260. Go to original source... Go to PubMed...
- Austin JHM, Kavita G, Aberle D, et al. Radiologic Implications of the 2011 Classification of Adenocarcinoma of the Lung. Radiology 2013; 266: 62-71. Go to original source... Go to PubMed...
- Russell PA, Wainer Z, Wright GM, et al. Does lung adenocarcinoma subtype predict patient survival? A Clinicopathologic Study Based on the New International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Lung Adenocarcinoma Classification. J Thorac Oncol 2011; 6: 1496-1504. Go to original source... Go to PubMed...
- Adami JG. On the classification of tumours. J Pathol Bacteriol 1903; 8(2): 243-259. Go to original source...
- Jones KD. Whence lepidic: the history of a Canadian neologism. Arch Pathol Lab Med 2013; 137: 1822-18244. Go to original source... Go to PubMed...
- Torres PP, Capobianco J, Montandon Júnior ME, Meirelles GS. Aspects of bronchioloalveolar carcinoma and of adenocarcinoma with a bronchioloalveolar component: CT findings. J Bras Pneumol 2012; 38(2): 218-225. Go to original source... Go to PubMed...
- Tsutani Y, Miyata Y, Nakayama H, et al. Appropriate sublobar resection choice for ground glass opacity dominant clinical stage IA lung adenocarcinoma: wedge resection or segmentectomy. Chest 2014; 145: 66-71. Go to original source... Go to PubMed...
- Weichert W, Warth A. Early lung cancer with lepidic pattern: adenocarcinoma in situ, minimally invasive adenocarcinoma, and lepidic predominant adenocarcinoma. Curr Opin Pulm Med 2014; 20: 309-316. Go to original source... Go to PubMed...
- Berry MF, Gao R., Kunder CA, et al. Presence of even a small ground-glass component in lung adenocarcinoma predicts better survival. Clin Lung Cancer 2017; 19: e47-51. Go to original source... Go to PubMed...
- Aherne EA, Plodkowski AJ, Montecalvo J, et al. What CT characteristics of lepidic predominant pattern lung adenocarcinomas correlate with invasiveness on pathology? Lung Cancer 2018; 118: 83-89. Go to original source... Go to PubMed...
- Araki K, Kidokoro Y, Hosoya K, et al. Excellent prognosis of lepidic-predominant lung adenocarcinoma: low incidence of lymphatic vessel invasion as a key factor. Anticancer Research 2014; 34: 3153-3156.
- MacMahon H, Naidich D, Goo JM, et al. Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017. Radiology 2017; 284(1): 228-243. Go to original source... Go to PubMed...
- Callister MEJ, Baldwin DR, Akram AR, et al. BTS Guidelines for the Investigation and Management of Pulmonary Nodules. Thorax 2015; 70(Suppl 2). Go to original source... Go to PubMed...
- Gandara DR, Aberle D, Lau D, et al. Radiographic Imaging of Bronchioloalveolar Carcinoma: Screening, Patterns of Presentation and Response Assessment. J Thorac Oncol 2006; 1: S20-S26. Go to original source...
- Akira M, Atagi S, Kawahara M, Iuchi K, Johkoh T. High-resolution CT findings of diffuse bronchioloalveolar carcinoma in 38 patients. Am J Roentgenol 1999; 173: 1623-1629. Go to original source... Go to PubMed...
- Ichinose J, Kohno T, Fujimori S, et al. Invasiveness and malignant potential of pulmonary lesions presenting as pure ground-glass opacities. Ann Thorac Cardiovasc Surg 2014; 20: 347-352. Go to original source... Go to PubMed...
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