Ces radiol. 2018, 72(4):247-253 | DOI: 10.55095/CesRadiol2018/033

Correlation between percentage of honeycombing on chest HRCT evaluated by the CALIPER automated program and visual identification by radiologistOriginal article

Martin Hyršl¹, Eva Kočová¹, Pavel Eliáš¹, Jiří Vaňásek¹, Jiří Jandura¹, Vladimír Bartoš², Jan Novosad³

¹ Radiologická klinika LF UK a FN, Hradec Králové

² Plicní klinika LF UK a FN, Hradec Králové

³ Ústav klinické imunologie a alergologie LF UK a FN, Hradec Králové

Purpose: The pilot study to investigate the correlation between the percentage of HRCT honeycombing captured by the CALIPER automatic program and the visual identification of this morph presence by five radiological examinations in patients with known interstitial pulmonary fibrosis (IPF).

Methods: 15 patients selected from the alphabetical list of patients from the Faculty Hospital Hradec Králové (FNHK) with established diagnosis of idiopathic pulmonary fibrosis (IPF). For 12 of them, the CALIPER program was analysed, followed by the evaluation of five radiologists from FNHK.

Results: The best ratio between sensitivity and specificity was achieved at a 3.5 percent representation of honeycomb in right lung, when the sensitivity was 80% and the specificity was 85.7%. 13% of patients evaluated had a significantly different interpretation of honeycomb presence.

Conclusion: Pilot studies have shown that the 3.5% threshold for the presence of honeycombing has 80% sensitivity and 85.7% specificity when is program CALIPER compared to the visual consensus of radiologists. For limitations in this study, we recommend further research.

Keywords: CALIPER, honeycombing, interstitial lung fibrosis

Accepted: August 15, 2018; Published: December 1, 2018  Show citation