Ces radiol. 2020, 74(4):259-263 | DOI: 10.55095/CesRadiol2020/038
SARS-CoV-2 pneumonia incidentally detection on 18F-FDG PET/CT in an asymptomatic patient during follow-up for esophagel cancerOriginal article
- 1 Oddělení nukleární medicíny LF UK a FN, Hradec Králové
- 2 Radiologická klinika LF UK a FN, Hradec Králové
Aim: To present a case report about 71-year-old man with a positive history of esophageal cancer with stable mediastinal and hilar lymph nodes metastases who underwent a follow-up 18F-FDG PET/CT imaging. The examination incidentally showed SARS-CoV-2 (COVID-19) pneumonia.
Method: The patient with esophageal cancer after treatment and stable mediastinal and hilar lymph nodes metastases underwent a follow-up 18F-FDG PET/CT examination. The patients was asymptomatic without cough or fever. The PET/CT scan was obtained 60 minutes after intravenous injection of 18F-FDG. The PET scan acquisition time was 2.5 minutes per bed position and seven bed positions were necessary. Contrast-enhanced CT (venous phase) provided both full CT evaluation (including intravenous and oral contrast) and PET attenuation correction.
Results: In addition to demonstrating stable 18F-FDG-avid metastases in mediastinal and hilar lymph nodes, the PET/CT incidentally detected 18F-FDG-avid bilateral pulmonary ground glass and subpleural opacities. The finding was suggestive of COVID-19 associated pneumonia. The infection of SARS-CoV-2 was subsequently confirmed by PCR test.
Conclusion: 18F-FDG PET/CT imaging correctly detected a latent COVID-19 pneumonia in an asymptomatic patient with a positive history of esophageal cancer and mediastinal and hilar lymph nodes metastases and led to a correct anti-epidemic arrangement.
Keywords: COVID-19, PET/CT, fluorodeoxyglucose, pneumonia
Grants and funding:
Podpořeno MZ ČR - RVO (FNHK, 00179906).
Accepted: December 15, 2020; Published: December 1, 2020 Show citation
ACS | AIP | APA | ASA | Harvard | Chicago | Chicago Notes | IEEE | ISO690 | MLA | NLM | Turabian | Vancouver |
References
- Vaidyanathan S, Patel CN, Scarsbrook AF, Chowdhury FU. FDG PET/CT in infection and inflammation - current and emerging clinical applications. Clin Radiol 2015; 70(7): 787-800.
Go to original source...
Go to PubMed...
- O'Malley J, Ziessman HA, Thrall JH. Nuclear medicine and molecular imaging: The Requisites, 5th edition. Philadelphia, USA: Elsevier 2020; 409-430.
- Amini H, Divband G, Montahaei Z, Dehghani T, Kaviani H, Adinehpour Z, Akbarian Aghdam R, Rezaee A, Vali R. A case of COVID-19 lung infection first detected by (18F)FDG PET-CT. Eur J Nucl Med Mol Imaging 2020; 47(7): 1771-1772.
Go to original source...
Go to PubMed...
- Ferrando-Castagnetto F, Wakfie-Corieh CG, García AMB, García-Esquinas MG, Caro RMC, Delgado JLC. Incidental and simultaneous finding of pulmonary thrombus and COVID-19 pneumonia in a cancer patient derived to 18 F-FDG PET/CT. New pathophysiological insights from hybrid imaging. Radiol Case Rep 2020; 15(10): 1803-1805.
Go to original source...
Go to PubMed...
- Rasilla J, Pernetty J, Cardona Arboniés RJ. Diagnosis of COVID-19 pneumonia in asymptomatic patients after an oncological PET/CT. Rev Esp Med Nucl Imagen Mol 2020; 39(5): 299-302.
Go to original source...
- Albano D, Bertagna F, Bertoli M, Bosio G, Lucchini S, Motta F, Panarotto MB, Peli A, Bengel FM, Giubbini R. Incidental findings suggestive of COVID-19 in asymptomatic patients undergoing nuclear medicine procedure in a high-prevalence region. J Nucl Med 2020; 61(5): 632-636.
Go to original source...
Go to PubMed...
- Altmayer S, Zanon M, Pacini GS, et al. Comparison of the computed tomography findings in COVID-19 and other viral pneumonia in immunocompetent adults: a systematic review and meta-analysis. Eur Radiol 2020; 30(12): 6485-6496.
Go to original source...
Go to PubMed...
- Revel MP, Parkar AP, Prosch H, et al. Covid-19 patients and the radiological department - advice from the European Society of Radiology (ESR) and the European Society of Thoracic Imaging (ESTI). Eur Radiol 2020; 20(9): 1-7.
Go to original source...
Go to PubMed...
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.