Ces radiol. 2026, 80(1):33-37 | DOI: 10.55095/CesRadiol2026/001

Sister Mary Joseph nodule: case study - metastasis of intra-abdominal cancers in the umbilical regionCase report

Lenka Červenková, Hana Pánková Petrášová

Klinika radiologie a nukleární medicíny, Fakultní nemocnice Brno

Korespondenční adresa:

MUDr. Hana Pánková Petrášová, Ph.D.

Klinika radiologie a nukleární medicíny LF MU a FN Brno

Jihlavská 20, 625 00 Brno

Konflikt zájmů: žádný.

Metastatic lesions located in the umbilical region, which have the location of the original tumor in the abdominal cavity, are also called "Sister Marie Joseph's nodule" after the nurse who first pointed out this symptom. We present the case of a patient coming in for an ultrasound examination with a presumed gangrenous umbilical hernia, which turned out to be an incidental finding of a metastatic umbilical lesion, which then led to the primary diagnosis of endometroid carcinoma. The paper also includes a summary of the basic information about this so-called Sister Mary Joseph's nodule, including its diagnosis and subsequent treatment.

Keywords: endometroid carcinoma, intra-abdominal carcinomas, Sister Mary Joseph sign, umbilical metastasis, Sister Mary Joseph nodule.

Received: October 18, 2025; Revised: October 18, 2025; Accepted: February 15, 2026; Published: May 1, 2026  Show citation